Dean of the University of Maryland School of Medicine (UMSOM). Mark T. Gladwin, MDannounced on May 1 that Bradley A. Maron, MD, associate professor of medicine at Brigham & Women’s Hospital (BWH) and Harvard Medical School (HMS) and co-director of the Pulmonary Vascular Disease Center at the VA Boston Healthcare System, was named co-director of the new University of Maryland Institute for Health Computing (UM -IHC), director of science operations for UM-IHC, as well as senior associate dean for precision medicine at UMSOM, effective May 1, 2023.
In his new role as co-director of UM-IHC, Maron will work with partners at the University of Maryland, Baltimore (UMB), the University of Maryland, College Park (UMCP), and the University of Maryland Medical System (UMMS ) to establish the new institute as an international leader in the interrelated fields of clinical analytics and computational biology, using advanced data science technologies. He will also lead efforts to build centers within the institution that focus on therapeutic target discovery, population health, pragmatic clinical trials, and a core educational curriculum that emphasizes scientific entrepreneurship.
Bradley A. Maron, MD
Launched in November 2022, UM-IHC seeks to leverage recent advances in network medicine, artificial intelligence (AI), and machine learning to create a world-class learning healthcare system that evaluates digitized health data both anonymised and secure to improve patient outcomes throughout the state of Maryland.
As Senior Associate Dean for Precision Medicine, Maron will oversee initiatives that strengthen UMSOM’s ability to pursue research that advances the school’s leadership in precision medicine, a new area of medicine that uses insights gained from profile biological and clinical aspects of a patient to prevent, diagnose, or treat disease. These initiatives will include acquiring funds for operational progress, building new partnerships with key federal health agencies such as the National Institutes of Health (NIH) and the Food and Drug Administration, identifying appropriate faculty recruits, and promoting of precision medicine approaches to clinical care. Working with the senior associate dean for undergraduate medical education, Maron will also ensure that precision medicine is represented in the medical school curriculum and that UMSOM is preparing students to lead research and clinical initiatives in this emerging area.
Maron is a recognized physician-scientist in the rapidly growing fields of precision medicine, network medicine, and computational data analytics. Currently, he is engaged as co-principal investigator in an ongoing study entitled “Network Medicine and Systems Pharmacology to Advance Precision Medicine in Combined Pulmonary Hypertension” and a second, as principal investigator, entitled “Personalized Protein-Protein Interactomas and Precision Medicine in ‘pulmonary arterial hypertension. He is also co-author of several articles published in leading journals for the American Heart Association, the American Thoracic Society and the Nature family discussing how multi-omics technologies can contribute to precision medicine
“Dr. Maron is a highly effective and strategic leader who is ideally suited to move this new institution forward,” said Gladwin, who is also vice president for medical affairs, UMB, and John Z. and Akiko K. Bowers Distinguished Professor, UMSOM. “His experience and entrepreneurial management skills are perfectly aligned with our new vision of using disruptive technology and embracing and leveraging the power of clinical analytics and precision medicine to improve patient care and deliver healthcare services to the population”.
In 2021, Maron was inducted into the American Society of Clinical Investigation, one of the oldest and most prestigious medical societies in the United States. At BWH, he was Vice President of Cardiovascular Life Sciences in the Division of Cardiovascular Medicine and Medical Director of the Cardiopulmonary Exercise Center. Additionally, he has received the Excellence in Tutoring Award, the Eleanor and Miles Shore Scholar in Medicine Fellowship, Chair’s Research Award, Distinguished Master Clinician Award and Master Clinician Award from BWH and HMS.
Maron is a widely published and NIH-funded investigator, co-author of more than 200 peer-reviewed articles and book chapters. His research focuses on understanding new molecular mechanisms involved in the pathobiology of cardiovascular diseases. He is currently the principal investigator on three major NIH project grants, totaling more than $1.6 million annually in funding. The American Heart Association, the National Scleroderma Foundation, the Pulmonary Vascular Research Institute and the National Institutes of Health supported his research.
In 2020, he led an international research program that resulted in a publication in Respiratory Medicine Lancet entitled “The association between pulmonary vascular resistance and clinical outcomes in patients with pulmonary hypertension: a retrospective cohort study”. This work has contributed to a change in the disease definition of pulmonary hypertension. His seminal paper on “NEDD9 Targets COL3A1 to Promote Endothelial Fibrosis and Pulmonary Arterial Hypertension” which was published in Science Translational Medicine, a branded journal of the American Association for the Advancement of Science, laid the groundwork for a US patent and implicated NEDD9 as an important mediator of pulmonary vascular fibrosis and thrombosis. He is also editor-in-chief of the seminal text “Pulmonary Hypertension: From Basic Science to Clinical Medicine” (Springer, 2016).
“We are in a transformative period for healthcare in Maryland, where building computational systems that use patient-level information to personalize disease prevention and treatment strategies is a reality,” Maron said. “The key is to build systems with the capacity to improve health, well-being and longevity for all of Maryland’s people – that’s our mission. I am extremely excited and fortunate to work with the co-directors of the University of Maryland, College Park and the University of Maryland Medical System in this endeavor. “
Maron is a graduate of Williams College and received his MD from Brown University’s Warren Alpert Medical School before completing an internal medicine residency at Boston Medical Center. He then completed cardiovascular medicine research and clinical fellowship programs at BWHarvard. Maron is certified by the American Board of Internal Medicine in cardiovascular medicine.
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